What Causes Gout?
To learn what causes gout, you can check the following list that shows the most common causes of this disease.
- Genetic Problems,
- Medical Conditions,
- Medications, and
- Dehydration
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Genetic Problems
Some people are more prone to developing gout due to their genes. Because they may inherit genes that cause them to make too much uric acid or have difficulty eliminating it from the body.
This genetic factor leads to higher levels of uric acid in the blood, which increases the risk of uric acid crystals forming in the joints and triggering painful gout attacks. If your parents or grandparents had gout, you're more likely to get it as well [6].
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Medical Conditions
The following health problems can increase uric acid levels and lead to gout, even if your diet is healthy.
- Obesity: Carrying extra weight puts more stress on the body and can cause gout. When someone is overweight or obese, there is more tissue and cells in the body, which can produce more uric acid as a waste product [7].
- High Blood Pressure: The kidneys have a harder time filtering out uric acid when blood pressure is high. The kidneys' job is to filter waste products like uric acid out of the blood. When blood pressure is high, there is more pressure on the kidneys, which makes it more difficult for them to effectively remove uric acid from the body [8].
- Diabetes: Diabetes affects how the body processes sugars, which can raise uric acid. When the body can't effectively manage sugar, it tries to get rid of the excess sugar through the kidneys. This increased workload for the kidneys makes it harder for them to remove uric acid [9].
- Kidney Disease: The kidneys play a key role in removing uric acid, so kidney problems like kidney stones increase the incidence of gout [10].
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Medications
Some common prescription drugs, like diuretics used for high blood pressure, can interfere with uric acid removal and cause gout. Diuretics work by helping the body remove excess water and salt. However, they can also interfere with the kidneys' ability to properly eliminate uric acid from the body [11].
When uric acid builds up in the bloodstream due to these medications, it can form painful crystals in the joints, leading to gout attacks.
You can always discuss any potential medication side effects with a healthcare professional, as they can adjust the treatment plan to help manage the risk of gout.
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Dehydration
Not drinking enough water builds up uric acid in the body and crystallizes in the joints. When the body doesn't have enough fluids, especially water, the kidneys should try harder to flush out the excess uric acid produced naturally and it leads to a higher uric acid in the bloodstream.
The elevated uric acid levels increase the risk of crystals forming in the joints, which triggers sudden and severe pain related to gout attacks.
Staying hydrated by drinking enough water can help the kidneys effectively remove uric acid and reduce the likelihood of developing gout [12].
Fortunately, there are various treatments for gout, like medications and dietary approaches, that can help control the symptoms.
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